Addressing the Threat of Drug-Resistant Tuberculosis: A by Institute of Medicine

By Institute of Medicine

Show description

Read Online or Download Addressing the Threat of Drug-Resistant Tuberculosis: A Realistic Assessment of the Challenge: Workshop Summary PDF

Similar infectious disease books

Physician's Guide to Arthropods of Medical Importance

Even within the such a lot industrialized countries, the illnesses as a result of universal and unique bugs pose a major hazard, making speedy and actual analysis and therapy important. Physician's advisor to Arthropods of scientific significance is the last word source for deciding on arthropods - together with forms of bugs, spiders, mites, ticks, and scorpions - and their damaging results on human wellbeing and fitness.

Human Parasitology

Human Parasitology emphasizes a scientific standpoint whereas incorporating sensible morphology, body structure, biochemistry, and immunology to reinforce appreciation of the varied implications of parasitism. Bridging the space among classical scientific parasitology texts and conventional encyclopedic treatises, Human Parasitology appeals to scholars drawn to the scientific facets of parasitology and people who require an outstanding beginning within the biology of parasites.

Parasite Diversity and Diversification: Evolutionary Ecology Meets Phylogenetics

The advance of molecular instruments has dramatically elevated our wisdom of parasite variety and the vectors that transmit them. From viruses and protists to arthropods and helminths, each one department of the Tree of existence bargains an perception into major, but cryptic, biodiversity. along this, the experiences of host-parasite interactions and parasitism have motivated many medical disciplines, equivalent to biogeography and evolutionary ecology, through the use of comparative equipment in accordance with phylogenetic info to resolve shared evolutionary histories.

Extra info for Addressing the Threat of Drug-Resistant Tuberculosis: A Realistic Assessment of the Challenge: Workshop Summary

Example text

WHO. 2008b. Anti-tuberculosis drug resistance in the world, fourth global report by the WHO/IUATLD Global project on anti-tuberculosis drug resistance surveillance. Geneva, Switzerland: WHO. WHO. 2008c. TB/HIV facts. pdf (accessed February 17, 2009). Zintl, P. 2008. Speaker ����������������������������������������������������������������������������� presentation at the Institute of Medicine Workshop on Addressing the Threat of Drug-Resistant Tuberculosis, Washington, DC, November 5. 7 million TB deaths occurred in 2006 alone (WHO, 2008a).

Among the 32 patients, 84 percent had a pair of isolates with discordant patterns, and 16 percent had a pair of isolates with identical patterns. Thus, the researchers concluded that among treated patients, 84 percent of drug resistance was transmitted and 16 percent acquired. Gao stated that new strategies are needed to block the transmission of MDR and XDR TB. , kanamycin, capreomycin, or amikacin), but not both. SOURCE: Gao, 2008. cussed in more detail below). However, implementing effective transmission control in resource-limited settings globally presents major challenges: • • Establishing community-based treatment outside a hospital cur­ rently is not feasible in some settings because the tradition and infrastructure for community care do not exist.

Without a vaccine and without early, accurate case detection and proper treatment, the MDR/XDR TB epidemic will be driven by transmission. 37 MDR TB TRANSMISSION Number of Patients (in thousands) 500 Estimated 489,000 new MDR TB cases each year 400 300 443 407 Estimated new, untreated cases Non-GLC cases 403 427 407 200 GLC cases 100 0 1 2004 21 16 16 2 2005 36 34 10 12 2007 2008 2 2006 Year FIGURE 3-1 MDR TB burden and patients in treatment. NOTES: The bars represent the number of new MDR TB cases in each year.

Download PDF sample

Rated 4.03 of 5 – based on 47 votes