Advances in Bladder Research by Tung-Tien Sun, Feng-Xia Liang, Xue-Ru Wu (auth.), Laurence

By Tung-Tien Sun, Feng-Xia Liang, Xue-Ru Wu (auth.), Laurence S. Baskin, Simon W. Hayward (eds.)

The objective of Bladder study Congress, San Francisco, California, April 23-25, 1998, was once to supply a discussion board for authoritative investigators who're actively excited about many of the disciplines which outline the top edges of bladder learn. it is necessary for such investigators to proceed to satisfy usually for the aim of discussing the newest advancements of their person fields, to investigate the importance of present study, to debate new strategies for unresolved difficulties, to seriously overview present theories, and to improve new theories and ways as wanted. the 2 and a part day assembly was once geared up into 5 part day classes, with every one consultation encompassing one among 5 issues: (1) Epithelial-Mesenchymal Interactions; (2) Ex­ tracellular Matrix and Muscle; (3) Nerves and Pharmacology; (4) an infection and Immunol­ ogy; and (5) Oncology. every one consultation was once brought via a moderator through 5 to 6 invited professional audio system with time for huge interplay from the members. late-afternoon poster periods allowed additional interactions among investigators. This booklet records the court cases of the Bladder study Congress. it really is organ­ ized into the 5 half-day periods of the assembly with moderators review and an edited transcription of discussions that each one presentation. i need to thank Sarah Burke and the workplace of constant clinical schooling, USCF; Joanne Hayward, Editorial Assistant; and Miriam Escamilla, Administrative Assis­ tant. i'm hoping you discover this source worthy. Laurence S. Baskin, M.D.

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Group A (n=2) underwent closure of the trigone without a reconstructive procedure. Group B (n=6) underwent reconstruction with a cellfree bladder shaped biodegradable polymer. Group C (n=6) underwent reconstruction using a bladder shaped biodegradable polymer that delivered autologous urothelial cells and smooth muscle cells. The cell populations had been separately expanded from a previously harvested autologous bladder biopsy. Preoperative and postoperative urodynamic and radiographic studies were performed serially.

J. , 65: 345, 1990. 76. : Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. , 211: 90,1994. 77. : p27Kipl, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. , 8: 9,1994. 78. : Patterns of splice variant CD44 expression by normal human urothelium in situ and in vitro and by bladder-carcinoma cell lines. Int. l. , 62: 449, 1995. 79. : The effects of dietary fatty acids on the proliferation of normal human urothelial cells in vitro.

These structures were tubularized and used to replace ureteral segments in each animal. 16 The results suggested that the creation of artificial ureters may be achieved in vivo using biodegradable polymers as transplanted cell delivery and native cell expansion vehicles. The malleability of the synthetic polymer allowed for the creation of cell-polymer implants manipulated into pre-formed tubular configurations. The combination of both smooth muscle and urothelial cell-polymer scaffolds is able to provide a template wherein a functional ureter may be created de novo.

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